pulmonaryfibrosis相关论文
The cell cycle inhibitor P21 promotes the development of pulmonary fibrosis by suppressing lung alve
The cell cycle inhibitor P21 has been implicated in cell senescence and plays an important role in the injury-repair pro......
肺纤维化是一种以肺实质重塑和胶原沉积为特征的不可逆性间质性肺病。近年来，不明原因导致的肺纤维化发病率和病死率呈上升趋势，其发......
Intervention effect of Danbei Yifei formula on pulmonary fibrosis based on urine metabolomics by UHP
Objective: Determine the urinary biomarkers and pathogenesis of pulmonary fibrosis rats, and elaborate the intervention ......
Protective Effect of Hydroxysafflor Yellow A on Bleomycin-Induced Pulmonary Inflammation and Fibrosi
Objective:To observe the effect of hydroxysafflor yellow A (HSYA),an active ingredient of a traditional Chinese herbal m......
Association of baseline pulmonary fibrosis with the outcome of PD-1 inhibitor in patients with advan
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目的 IκB Kinase-β is critical regulator in the activation of nuclear factor-κB (NF-κB), a transcription factor relat......
Chop Deficiency Protects Mice against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macroph
目的 Idiopathic pulmonary fibrosis (IPF) is a severe health problem worldwide and has one of the poorest prognoses.C/EBP......
OPG may protect bleomycin-induced pulmonary fibrosis by inhibiting SMAD2/3 dependent TGF-β1 activati
目的 Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and lethal pathological process with limited therapeu......
目的 Pulmonary fibrosis is a progressive disease with poor prognosis and treatment.It is characterized by lung fibroblas......
Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-i
目的 Baicalin has been reported to have anti-fibrosis effect； however, its mechanism still remains to be elucidated.Adeno......
目的 Idiopathic pulmonary fibrosis (IPF) is a chronic devastating disease with poor prognosis.Multiple pathological proc......
Caveolin-1 deficiency causes pulmonary fibrosis alters energy metabolism and induces endoplasmic ret
目的 Caveolin-1 (Cav-1), a major structural protein of caveolae, is involved in many physiological and pathophysiologica......
目的 Idiopathic pulmonary fibrosis (IPF) is a progressive disorder with poor prognosis. The treatment options for IPF ar......
目的 To investigate the molecular mechanism of miR-338-5p in the pathological process of pulmonary fibrosis. 方法 we fir......
Suberoylanilide Hydroxamic Acid Attenuates Paraquat-induced Pulmonary Fibrosis by Preventing Smad7 f
目的 Recent evidence suggests that a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), has anti-fib......
Ni (Ⅱ) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating Akt signa
目的 Ni is a kind of harmful heavy metals in particulate matter. We previously reported that Ni ions are strongly associ......
目的 The objectives of the present study were to investigate whether NALP3 inflammasome activation is involved in H2O2-m......
目的 Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized of epithelial phenotypic changes and fib......
目的 In this study,we investigated the potential therapeutic effect of GA on pulmonary fibrosis in a ratmodel with bleom......
Mobilization of bone marrow stem cells by G-CSF protects mice from bleomycin induced pulmonary fibro
Background: Pulmonary fibrosis is a progressive disorder characterized by the excessive proliferati on of fibroblasts an......
Aim To investigate the effects of general ginsenoside on the pulmonary fibrosis in mice.Methods All the animals were div......
In silico analysis and experimental validation of active compounds from Rhodiola rosea L.amelioratin
Aim Rhodiola rosea L.possesses a wide range of pharmacological properties including lungprotective,and it has been imple......
The biosecurity assessment of nanosized SiO2 has been widely drawn the attentions from public.Recent toxicological studi......
Blockage of autophagic flux in alveolar epithelial cells is essential for ultrafine particle-induced
Ultrafine particles(UFPs)are capable of inducing pulmonary fibrosis(PF);however,the underlying molecular mechanisms have......
Cell-surface Translocation of Annexin A2 contributes to bleomycin-induced pulmonary fibrosis by medi
Bleomycin,a widely used cancer drug,may give rise to a serious side effect,pulmonary fibrosis which is associated with s......
Microcarrier as pulmonary drug delivery system for treatment of pulmonary fibrosis induced by paraqu
It has been shown that endoplasmic reticulum stress (ERS) is involved in the pulmonary fibrosis.Fluorofenidone (AKF) is ......
Purpose: Idiopathic pulmonary fibrosis(IPF)is a devastating and irreversible lung disease with few treatment options and......
OPG may protect bleomycin-induced pulmonary fibrosis by inhibiting SMAD2/3 dependent TGF-β1 activati
RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and lethal pathological process with limited th......
We sought to explore the treatment effects and the repair mechanisms of bone marrow derived mesenchymal stem cells (MSCs......
Objective: To observe the protective effect and the underlying mechanism of total ginsenosides on bleomycin-induced pulm......
Objective: To investigate the effect of Osthole (Ost) on TGF-β1/Smad3 signaling pathway in pulmonary arterial hypertens......
Aim: Idiopathic pulmonary fibrosis (IPF), the most prevalent idiopathic interstitial pneumonia, has a median survival of......
Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fib
OBJECTIVE Epithelial-mesenchymal transition (EMT) is a phenotype conversion that plays a critical role in the developmen......
Inhibitory effect and mechanism of calcitonin gene-related peptide on bleomycin-induced lung fibrosi
Aim: Calcitonin gene-related peptide (CGRP) is a predominant neurotransmitter in sensory nerves.It has been reported tha......
Total glucosides of Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis by inhibitin
Aim: Pulmonary fibrosis (PF) is a major cause of lung failure, but treatment remains ineffective.Our previous studies su......
Anti-fibrotic effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl.Leaf in pulmonary fib
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Rac1 is an important signaling molecule in cigarette smoke-stimulated alveolar epithelial-mesenchyma
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Our previous study has found that CGRP inhibited proliferation of PASMCs induced by hypoxia via inactivation of ERK1/2 s......
Background: Pulmonary fibrosis is a progressive disease with poor prognosis and treatment.It is characterized by lung fi......
Objective: To investigate the antioxidant effects of Bach1 siRNA on BLM induced pulmonary Fibrosis.Methods: Mouse lung f......
Amelioration of bleomycin-induced pulmonary fibrosis of rats by an aldose reductase inhibitor, epalr
Aldose reductase(AR)is known to play a crucial role in the mediation of diabetic and cardiovascular complications.Recent......
Surface sperimidine functionalized, fluorofenidone-loaded PEG-PLGA nanoparticles for enhanced treatm
Despite significant efforts have been made to prevent paraquat (PQ)-induced pulmonary fibrosis,including corticosteroids......
Connective tissue growth factor (CTGF) stimulates proliferation,migration, and differentiation of lu
It is well known that paraquat (PQ) poisoning can cause severe lung injury during the early stages of exposure, finally ......
Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fib
Background and Purpose: Epithelial-mesenchymal transition (EMT) is a phenotype conversion that plays a critical role in ......
Objective: To establish murine model of pulmonary fibrosis by Bleomycin and screen the anti-pulmonary fibrosis activity ......
miR-486 Is Downregulated during Pulmonary Fibrosis and Mediates TGFbeta-induced Lung Fibroblast Acti
Emerging evidence suggests that microRNAs (miRNAs) play a critical biological role in a variety of pathophysiological pr......
We sought to explore the treatment effects and the repair mechanisms of bone marrow derived mesenchymal stem cells (MSCs......
Total glucosides of Danggui Buxue Tang inhibits bleomycin-induced pulmonary fibrosis via targeting H
Objective: Danggui Buxue Tang (DBT) is a classical traditional Chinese herbal formula.Previous studies showed that total......
